Hans wanted me to talk more specifically about some of the features I used at
CarpeChaos.com, and now that our second issue is out, I've got enough of a lull to spend some time on the forums.

What may be the most noteworthy is our integration with Drupal. There's
an open source module on Drupal.org that includes all the features we used on our site. It allows us to easily create books with 720p and 1080p sized pages, and use adaptive zoom to switch between them. By default, each page contains only one image(at two resolutions of course), but there's a per-page XML overrides that allow you to do anything you want.

Once you've created a page, you can add it to a chapter, and you can add chapters to books.
Each page has it's own XML override, and each chapter does as well. Currently the settings for all books have to be the same, but in a future release (hopefully around August), you'll be able to override attributes of the book tag on a per-attribute per-book basis.
It's also integrated with the ad module, which means ad pages are dynamically run in all our books, and can be added or expired site-wide without changing any of the books.
It takes us less than 15 minutes to publish a 15 page book.
Other features that I'm particular proud of, include:
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Adaptive zoom so users can see our images exclusively in their native resolutions, and important feature, since much of our text is embedded in jpegs, and scaling those images makes them hard to read.
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SWFaddress links are automatically generated pointing to all our chapters and pages
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Mouse drag before 2.0.9 I hacked together a pretty decent implementation of mouse drag before it was so well supported in 2.0.9, but that's nothing too special since it's much more standard now.
We're planning to upgrade to Megazine 2.0.9 or 2.0.10 later this summer to take advantage of the new mouse_drag features.