Today there's no way for an user to know if there's a link on a region at page, unless he hovers the region(using overlay attribute). What about create an attribute for "border-color" ?
It would be possible to create an "area" region with a border blinking , so the user will know that there's a link there.
I'm send you below an example of this.
Take a look at the two banners on the right bottom. There are a border blinking and it works with zoom mode too.
http://tinyurl.com/dz3b4e